Hear the latest on how supercomputing for the masses is changing the world. We will look at some of the one- to three-orders of magnitude faster killer apps and see how they do it. We will discuss specific mapping to GPGPU hardware and techniques for high performance and near-linear scalability both within and across multiple GPGPUs. We will also consider software investment and the decades long longevity of some successful massively parallel Investments in multithreaded software, scalability, balance metrics, lack of consensus on programming models, and lifecycle considerations.